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目的分析对反流性食管炎患者行莫沙比利+奥美拉唑治疗的效果。方法择取2012年3月至2014年12月本院收治的反流性食管炎患者120例为研究对象,随机分成两组,对照组60例,临床中给予莫沙比利单一用药治疗,观察组60例,采用莫沙比利+奥美拉唑治疗。结果观察组患者的治疗有效率(96.7%)高于对照组(85.0%),两组比较差异具有统计学意义(P<0.05);观察组患者治疗后的生活质量总体健康评分为(38.44±8.67),对照组为(25.56±7.46),观察组高于对照组(P<0.05)。结论采用莫沙比利和奥美拉唑联合治疗反流性食管炎效果明显,安全性高,可显著提高临床疗效和生活质量,值得临床推广应用。
Objective To analyze the effect of mosapride + omeprazole in patients with reflux esophagitis. Methods A total of 120 patients with reflux esophagitis who were treated in our hospital from March 2012 to December 2014 were selected and randomly divided into two groups. The control group was given 60 cases of single-drug treatment of mosapride. Group 60 cases, the use of mosapride + omeprazole treatment. Results The effective rate of treatment in observation group was significantly higher than that in control group (96.7% vs 85.0%, P <0.05), and the overall health score of quality of life after treatment in observation group was (38.44 ± 8.67) in the control group and (25.56 ± 7.46) in the control group, higher in the observation group than in the control group (P <0.05). Conclusion The combination of mosapride and omeprazole in the treatment of reflux esophagitis has obvious effect and high safety, which can significantly improve the clinical efficacy and quality of life, which is worthy of clinical application.