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目的了解广西南宁市男男性行为人群(MSM)艾滋病病毒(HIV)、梅毒、单纯疱疹病毒Ⅱ型(HSV-2)新发感染率,分析队列保持的影响因素,为南宁市MSM艾滋病预防策略和措施的制定和调整提供科学依据。方法利用滚雪球法招募研究对象,分别在基线调查后的6个月和12个月对MSM进行随访,随访内容包括问卷调查和HIV、梅毒、HSV-2检测。结果 12个月随访时,MSM人群HIV新发感染率为1.1/100人年(95%CI=0～3.3),梅毒新发感染率为6.8/100人年(95%CI=2.1～11.5),HSV-2新发感染率为5.2/100人年(95%CI=1.0～9.3);多因素logistic回归分析结果表明,6个月能随访到(OR=12.597)、在南宁市居住时间≥1年(OR=2.831)、最近6个月与女性发生过性行为(OR=5.359)是MSM队列保持的独立影响因素。结论南宁市MSM人群HIV新发感染率低于全国其他地方报道;队列保持率较低,参加6个月随访、南宁市居住时间长、最近6个月与女性发生过性行为是此次研究队列保持的独立影响因素。
Objective To investigate the new infection rates of HIV, syphilis and herpes simplex virus type 2 (HSV-2) among men who have sex with men (MSM) in Nanning, Guangxi and analyze the influencing factors of cohort maintenance. Measures to formulate and adjust to provide a scientific basis. Methods The subjects were recruited by the snowball method. MSM was followed up at 6 months and 12 months after baseline survey. The follow-up survey included questionnaires, HIV, syphilis and HSV-2. Results The rate of new HIV infection in MSM was 1.1 / 100 years (95% CI = 0-3.3) at 12-month follow-up. The new infection rate of syphilis was 6.8 / 100 years (95% CI = (95% CI = 1.0 ~ 9.3). The results of multivariate logistic regression analysis showed that patients were followed up for 6 months (OR = 12.597), lived in Nanning for ≥ 1 year (OR = 2.831). The most recent sexual intercourse with females in the past 6 months (OR = 5.359) was an independent factor for the maintenance of MSM cohort. Conclusions The prevalence of HIV infection in MSM population of Nanning City is lower than that reported in other parts of the country. The cohort maintenance rate is low. After 6-month follow-up, Nanning City has a long living period and has had sexual intercourse with women in recent 6 months. Maintain the independent factors.