近年,文献中广泛讨论了在类肉瘤病人检测血清血管紧张素转化酶(serum angiotensin-convertingenzyme,SACE)的价值。未经治疗的病人检测1次SACE,能了解疾病的活动性,而一系列检测则可进一步提供与病程相当一致的资料。作者以 SACE 检测与2年以上的临床观察对比来评价一组类肉瘤病人。伴有结节性红斑者预后较好,且显示一种特殊的SACE 型式,因而作者将此类病人及使用皮质类固醇治疗的病人除外。本组33例,确诊后至少随访2年,定期进行胸部X 线检查和 SACE 检测。根据观察期间 SACE 升高 In recent years, the literature discusses the value of detecting serum angiotensin-convertingenzyme (SACE) in sarcoidosis patients. Untreated patients detect SACE once to understand the disease’s activity, and a series of tests provide further information on the duration of the disease. The authors compared a group of sarcoid-like patients with SACE and more than 2 years of clinical observation. Patients with nodular erythema have a better prognosis and show a specific type of SACE, with the exception of those patients who are treated with corticosteroids. The group of 33 cases, at least 2 years follow-up after diagnosis, regular chest X-ray examination and SACE detection. SACE increased during the observation period