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定量病理学是用各种手段和分析方法在定性研究的基础上进一步从量化角度阐明疾病的病因、发病机理、发生发展规律及病变形态、机能和代谢特征的一门科学，是传统病理学科的进一步发展、完善和补充［１］。近来定量病理学应用于大肠癌的研究取得了很大进展，成为大肠癌研究的重要领域之一。本文就形态结构定量、ＤＮＡ定量、核仁组成区相关嗜银蛋白（ＡｇＮＯＲｓ）定量、分子病理学定量、免疫组化定量及三维结构重建等应用于大肠癌的研究作一综述
Quantitative pathology is a science that further quantifies the etiology, pathogenesis, occurrence and development of disease, and the shape, function, and metabolic characteristics of disease on the basis of qualitative research using various means and analytical methods on the basis of qualitative research. It is a traditional pathology discipline. Further develop, improve, and supplement [1]. Recent advances in the study of quantitative pathology in colorectal cancer have made great progress and have become one of the important areas for the study of colorectal cancer. This review focuses on the research of quantification of morphological structure, DNA quantification, AgNORs quantification, molecular pathology quantification, immunohistochemical quantification and three-dimensional structure reconstruction for colorectal cancer.