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1985～1992年英国阴道镜与宫颈病理学会对记录在案的来自24个中心的49名妇女进行了随访及回顾性研究。患者因患CIN而接受局部治疗,以后发展成为宫颈浸蚀癌。调查结果表明:49人中42例患鳞癌,6人患腺鳞癌,1人患腺癌。Ia期8例,Ib期24例,Ⅱ～Ⅳ期8例。13人已死亡。其中25例曾行激光治疗,10例行冷凝治疗,2例行电灼术,2例行冷冻治疗。19例在第1次随访或1年内确诊患癌。有5例在治疗5年以后才发生浸蚀癌。
Between 1985 and 1992, the British Colposcopy and Cervical Pathology Society conducted a follow-up and retrospective study of 49 women from 24 centers who were recorded. Patients suffering from CIN and receiving local treatment, later developed into cervical erosion. The survey results show that 42 of 49 people have squamous cell carcinoma, 6 have adenosquamous carcinoma and 1 have adenocarcinoma. 8 cases in stage Ia, 24 cases in stage Ib and 8 cases in stage II-IV. Thirteen people have died. Among them, 25 cases had laser treatment, 10 cases were treated by condensation, 2 cases were treated by cautery and 2 cases were treated by cryotherapy. 19 cases were diagnosed with cancer in the first follow-up or within 1 year. Five patients developed erosional cancer after five years of treatment.