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四亚甲基二砜四胺(毒鼠强,TETS)属神经毒性灭鼠剂,对成人的LD50为0.1mg/kg,其中毒机制可能通过阻断γ氨基丁酸受体而导致惊厥发作[1]。毒鼠强中毒至今尚无特效解毒药。研究表明[2]:毒鼠强中毒患者经一次血液灌流(HP)治疗后,体内毒物浓度可降低30%～50%。为了进一步证实HP对毒鼠
Tetramethylene disulfonamide (TETS) is a neurotoxic rodenticide with an LD50 of 0.1 mg / kg for adults, and its toxic mechanism may lead to seizures by blocking the γ-aminobutyric acid receptor [ 1]. Tetramine poisoning has no effective antidote. Studies have shown that [2]: toxic tetramine poisoning in patients after a hemoperfusion (HP) treatment, the body toxic concentrations can be reduced by 30% to 50%. In order to further confirm the HP on tetramine