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为进一步探讨ＮＯ与妊高征发病的关系， 通过Ｇｒｅｉｓｓ 方法测定了妊高征与正常对照孕妇外周静脉血与脐静脉血ＮＯ 代谢产物ＮＯ－２ ／ＮＯ－３ 水平， 结果：妊高征组与对照组母血间ＮＯ－２ ／ＮＯ－３ （１０－６６ ±３－３９；１１－００ ±２－４７ μｍｏｌ／Ｌ） 和脐血间（２－７８ ±２－７９；３－７８ ±３－２３ μｍｏｌ／Ｌ） 比较， Ｐ 均＞ ０－０５， 无明显差异。但妊高征组内和正常组内ＮＯ－２ ／ＮＯ－３ 比较； Ｐ均＜０－０１， 有显著差异。新生儿出生体重与ＮＯ－２ ／ＮＯ－３ 经相关关系分析， Ｒ＝０－１６， Ｐ＞０－０５， 无明显相关性。提示： ＮＯ与妊高征的关系尚不清楚， 其是否在妊高征发病中起作用需进一步探讨。
In order to further explore the relationship between NO and the pathogenesis of PIH, the NO metabolite NO-2 / NO-3 levels in peripheral blood and umbilical venous blood of PIH and normal pregnant women were determined by Greiss method. Results: The levels of NO-2 / NO-3 (10-66 ± 3-39; 11-00 ± 2-47 μmol / L) and umbilical cord blood (2-78 ± 2-79; 3-78 ± 3 -23 μmol / L), P> 0-05, no significant difference. However, there were significant differences in NO-2 / NO-3 levels between PIH group and normal group (P <0-01). Neonatal birth weight and NO-2 / NO-3 correlation analysis, R = 0-16, P> 0-05, no significant correlation. Tip: The relationship between NO and PIH is not clear whether its role in the pathogenesis of PIH needs further study.