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本文对肝癌高发区不同人群进行血清铁蛋白测定,结果肝癌组的血清铁蛋白值显著高于急肝组(P<0.05),非常显著高于慢肝组、正常组(P<0.001);慢肝组与正常组无显著差异(P>0.05),急肝组的铁蛋白值显著高于慢肝组与正常组(P<0.01)。在肝癌组中10例AFP 阴性者7例铁蛋白值增高,结果提示:血清铁蛋白测定有助于肝癌的诊断,尤其对 AFP 阴性肝癌的诊断;血清铁蛋白可作为反应肝细胞损伤的指标之一,亦可用于肝癌与慢肝的鉴别诊断。
In this study, serum ferritin was measured in different populations with high incidence of liver cancer. Results Serum ferritin levels in the liver cancer group were significantly higher than that in the acute liver group (P<0.05), which was significantly higher than that in the slow liver group and normal group (P<0.001); There was no significant difference between the liver group and the normal group (P>0.05). The ferritin value in the acute liver group was significantly higher than that in the slow liver group and the normal group (P<0.01). In the HCC group, 7 cases of AFP-negative patients showed an increase in ferritin value. The results suggest that serum ferritin determination is helpful for the diagnosis of liver cancer, especially for the diagnosis of AFP-negative liver cancer; serum ferritin can be used as an indicator of liver cell injury. First, it can also be used for the differential diagnosis of liver cancer and slow liver.