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目的分析Turner综合征(Turner Syndrome,TS)患者的心理特征,为TS患者心理干预提供临床依据。方法选择确诊的TS患者48例,其中体质指数(BMI)≥25 kg/m223例为TSⅠ组,BMI<25 kg/m225例为TSⅡ组;另选择健康儿童20例为对照组。所有研究对象行一般情况、染色体核型及心理特征评定,评分采用广州市惠爱医院精神科教研室推荐的症状自评量表(SCL-90)、抑郁自评量表(SDS)和焦虑自评量表(SAS),所有量表均由研究对象本人独立完成,由广州惠爱医院精神科教研室统一分析。结果 TSⅠ组和II组患者SCL-90躯体化、人际敏感、抑郁症状和焦虑症状评分均显著高于对照组(P<0.05),而强迫症状、敌对症状、偏执症状、恐怖症状和精神病性评分与对照组比较差异无统计学意义(P>0.05);TSⅠ组SCL-90评分和II组比较差异无统计学意义(P>0.05);TSⅠ组和TSⅡ组SDS和SAS评分均显著高于对照组(P<0.05),但TSⅠ组和TSⅡ组间评分差异无统计学意义(P>0.05)。结论 TS患者的心理特征为躯体化、敏感、偏执、抑郁和焦虑,BMI变化不增加TS患者心理异常。
Objective To analyze the psychological characteristics of patients with Turner Syndrome (TS) and provide the clinical basis for psychological intervention in patients with TS. Methods Totally 48 patients with TS were selected. Twenty-two patients with TSB≥25 kg / m 2 were selected as TS Ⅰ group, BⅡ <25 kg / m2 as TSⅡ group, and 20 healthy children as control group. All subjects were evaluated in terms of general conditions, karyotypes and psychological characteristics. SCL-90, Self-rating Depression Scale (SDS) and Self-rating Anxiety Scale Scale (SAS), all scales were independently completed by the research object, by the Department of Psychiatry, Guangzhou Huanai Hospital, a unified analysis. Results The scores of somatization, interpersonal sensitivity, depression and anxiety were significantly higher in TSⅠgroup and II group than those in control group (P <0.05), while the compulsive symptoms, hostile symptoms, paranoid symptoms, horror symptoms and psychotic scores There was no significant difference between the two groups (P> 0.05). There was no significant difference between the two groups (P> 0.05). The scores of SDS and SAS in TS Ⅰ group and TS Ⅱ group were significantly higher than those in control group (P <0.05). However, there was no significant difference between TS Ⅰ and TS Ⅱ (P> 0.05). Conclusion The psychological characteristics of TS patients are somatization, sensitivity, paranoid, depression and anxiety. The change of BMI does not increase the psychological abnormality of TS patients.