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目的探讨影响宫腔内人工授精(IUI)的影响因素,为提高IUI妊娠率提供信息支持。方法回顾性分析2011年10月~2014年4月在武汉市第一医院生殖中心接受IUI治疗的88对夫妇,共进行了159个周期,分组比较患者的一般情况、内膜厚度和男方精液等情况。结果按女方年龄分组,<35岁组的不孕年限相对较短[(1.99±1.31)年vs(3.94±2.08)年],处理后男方精液前向运动精子总数较多[(34.53±25.80)×106/ml vs(18.08±18.51)×106/ml],两者比较,差异有统计学意义(P<0.05)。<35岁组妊娠率高于≥35岁组(10.5%vs 5.9%),但差异无统计学意义(P>0.05);按是否促排卵分组,促排卵周期的子宫内膜厚度较自然周期薄[(9.15±2.16)mm vs(10.13±2.02)mm],差异有统计学意义(P<0.05),促排卵周期的临床妊娠率高于自然周期(11.5%vs 7.9%),但差异无统计学意义(P>0.05)。结论促排卵周期人工授精临床妊娠率高于自然周期。
Objective To investigate the influencing factors of intrauterine insemination (IUI) and to provide information for improving the pregnancy rate of IUI. Methods A retrospective analysis of 88 couples who underwent IUI treatment at the Reproductive Center of the First Hospital of Wuhan from October 2011 to April 2014 was conducted for 159 cycles in which the general condition of the patients, Happening. The results were grouped according to the age of the women. The infertility duration of the 35-year-old group was relatively short (1.99 ± 1.31) years vs (3.94 ± 2.08) years. × 106 / ml vs (18.08 ± 18.51) × 106 / ml], the difference was statistically significant (P <0.05). The pregnancy rate in the 35-year-old group was higher than that in the 35-year-old group (10.5% vs 5.9%), but the difference was not statistically significant (P> 0.05). The endometrial thickness of the ovulation- (9.15 ± 2.16) mm vs (10.13 ± 2.02) mm], the difference was statistically significant (P <0.05). The clinical pregnancy rate in ovulation induction period was higher than that in natural period (11.5% vs 7.9%), but the difference was not statistically significant Significance (P> 0.05). Conclusion Ovarian cycle artificial insemination clinical pregnancy rate higher than the natural cycle.