论文部分内容阅读
在医学遗传方面:比如将RFLP 寡核酸探针,尤其是体外基因扩增法、斑鱼杂交法等应用于人、β地中海贫血、血友病的产前诊断,以及胰岛素5’端RFLP,αPOA 基因的RFLP 等工作均已达到基因水平。溶酶体病、17羟化酶、21羟化酶等应用于产前诊断,HpLc 气相色谱等方法的应用反映了生化遗传学的工作有了新的进展。各种显带技术及高分辨率显带技术已被较广泛地应用,显示了细胞遗传学的研究已达到了新的水平。对出生缺陷的监测,对NTD,智力低下,先天聋哑等遗传病的防治都作了大量的工作。
In medical genetics: For example, the application of RFLP oligonucleotide probes, especially in vitro gene amplification method, hybridization of grouper, etc., to human, beta thalassemia, hemophilia prenatal diagnosis, and insulin 5 ’RFLP, alphaPOA Gene RFLP and other work have reached the genetic level. The application of lysosomal diseases, 17-hydroxylase and 21-hydroxylase in prenatal diagnosis and HpLC gas chromatography reflects the new progress of biochemical genetics. A variety of banding techniques and high-resolution banding techniques have been more widely used, showing that the study of cytogenetics has reached a new level. The monitoring of birth defects, NTD, mental retardation, genetic diseases such as deaf and deaf have done a lot of work.