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目的探讨早期气管插管在抢救急性重症有机磷农药中毒中对患者预后的影响。方法随机把43例急性重症有机磷农药中毒患者分为治疗组(根据临床症状早期对其进行气管插管)和对照组(在呼吸衰竭严重时或血气分析等检查后才进行气管插管),其余基础治疗相同,观察患者临床症状、临床体征、病死率等指标,并进行统计学分析。结果急性重症有机磷农药中毒患者气管插管的时机不同,患者临床症状、临床体征的改善,病死率差异有明显的统计学意义。治疗组患者病死率为13%;对照组患者病死率为35%(P<0.05)。结论根据患者临床症状对急性有机磷农药中毒早期气管插管能够达到改善患者临床症状、临床体征、有效降低急性重症有机磷农药中毒的病死率,具有良好的临床意义,值得临床推广应用。
Objective To investigate the effect of early tracheal intubation on the prognosis of patients with acute severe organophosphorus pesticide poisoning. Methods Forty-three patients with acute severe organophosphorus pesticide poisoning were randomly divided into treatment group (intratracheal intubation according to clinical symptoms early) and control group (intubation only after severe respiratory failure or blood gas analysis) The rest of the same basic treatment, observation of clinical symptoms, clinical signs, mortality and other indicators, and statistical analysis. Results The timing of endotracheal intubation was different in patients with acute severe organophosphorus pesticide poisoning. The clinical symptoms, clinical signs and mortality were significantly different among the patients. The mortality rate was 13% in the treatment group and 35% in the control group (P <0.05). Conclusion According to the clinical symptoms of patients with acute organophosphorus pesticide poisoning early tracheal intubation can improve clinical symptoms and clinical signs, and effectively reduce the mortality of acute severe organophosphorus pesticide poisoning, has a good clinical significance, it is worth promoting the clinical application.