论文部分内容阅读
目的探讨心脏肌钙蛋白Ⅰ(cTnI)测定对病毒性心肌炎的诊断价值及其临床意义。方法选择南阳医学高等专科学校第一附属医院2006年12月至2010年12月期间收治的病毒性心肌炎患者70例及同期健康体检者60例,采用固相层析免疫法测定患者血清cTnI水平,同时测定心肌酶谱作为对照。结果病毒性心肌炎患者的血清cTnI阳性率较肌酸激酶同工酶(CK-MB)有明显升高,差异有统计学意义(P<0.05);cTnI的敏感性和特异性均高于CK-MB,差异有统计学意义(P<0.05)。结论测定血清cTnI对于诊断病毒性心肌炎具有较高的价值,其特异性和敏感性均高于CK-MB,可作为诊断和预测心肌炎较好的指标之一。
Objective To investigate the diagnostic value of cardiac troponin Ⅰ (cTnI) in viral myocarditis and its clinical significance. Methods Seventy patients with viral myocarditis and 60 healthy volunteers admitted to the First Affiliated Hospital of Nanyang Medical College from December 2006 to December 2010 were enrolled in this study. Serum levels of cTnI were determined by solid-phase chromatography, Simultaneous determination of myocardial enzymes as a control. Results The positive rate of serum cTnI in patients with viral myocarditis was significantly higher than that of creatine kinase (CK-MB), the difference was statistically significant (P <0.05). The sensitivity and specificity of cTnI were higher than that of CK- MB, the difference was statistically significant (P <0.05). Conclusions The serum cTnI is of high value in the diagnosis of viral myocarditis, its specificity and sensitivity are higher than that of CK-MB, which can be used as a good indicator of diagnosis and prediction of myocarditis.