Cam profiles play an important part in the performance of cam mechanisms.Syntheses of cam profile designs and dynamics of cam designs are studied at first.Then,a cam profile design optimization model based on the six order classical spline and single DOF (degree of freedom) dynamic model of single-dwell cam mechanisms is developed.And dynamic constraints such as jumps and vibrations of followers are considered.This optimization model,with many advantages such as universalities of applications,conveniences to operations and good performances in improving kinematic and dynamic properties of cam mechanisms,is good except for the discontinuity of jerks at the end knots of cam profiles which will cause vibrations of cam systems.However,the optimization is improved by combining the six order classical spline with general polynomial spline which is the so-called trade-offs.Finally,improved optimization is proven to have a better performance in designing cam profiles.