庆大霉素的临床应用极为广泛,其毒副作用发生率较高,已引起不少严重后果,现就其一些少见毒副作用加以简介。一、过敏性休克庆大霉素最严重的副作用是速发型过敏性休克肌肉松驰作用。临床表现与其它药物所引起的过敏性休克类同,主要为呼吸道阻塞及微循环障碍症状。休克常发生在首次注射或连续用药过程中。二、严重急性溶血性贫血王氏报道一患儿。男,2.5岁,拟诊急性肠炎给庆大霉素3万u 静脉滴注3h 后,突然寒战,高热、面色苍白,四肢厥冷,皮肤轻度黄染,心率50次 The clinical application of gentamicin is very extensive, its high incidence of toxic side effects, has caused many serious consequences, is to introduce some of its rare toxic side effects. First, anaphylactic shock The most serious side effect of gentamicin is the immediate onset of anaphylactic shock muscle relaxation. Clinical manifestations and other drugs caused by the same type of anaphylactic shock, mainly for airway obstruction and microcirculation symptoms. Shock often occurs in the first injection or continuous medication process. Second, severe acute hemolytic anemia Wang reported a child. Male, 2.5 years old, diagnosed with acute enteritis to gentamicin 30000 u intravenous infusion 3h, a sudden chills, high fever, pale, limbs Jueleng, mild yellow skin, heart rate 50