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Purpose: To compare posterior capsule opacification (PCO) after cataract surge ry with implantation of two silicone intraocular lenses (IOLs) with different de signs. Methods: We carried out a prospective, clinical study of 116 patients ran domized to standardized phacoemulsification with implantation of CeeOnEdge (n=57 ) or SI40NB (n=59) IOLs. The follow-up period was 3 years. To evaluate PCO morp hologically, digital images were obtained and analysed using evaluation of poste rior capsule opacification computer software (EPCO). The neodymium:YAG (Nd:YAG) capsulotomy rate was recorded. Results: At 2 and 3 years, the eyes with SI40NB I OLs had significantly more PCO than those with the CeeOn Edge IOLs (p=0.00014 an d p=0.002). Nine Nd:YAG capsulotomies were performed in the SI40NB group and non e in the CeeOn Edge group. This difference was statistically significant (p=0.00 3). In some patients a regression of PCO was noticed and confirmed usingEPCO. St atistically less PCO was noted when the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and s tatistically significant difference in PCO development between CeeOn Edge and SI 40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the opt ic is a more important factor in IOL design than IOL material in the prevention of PCO.
Methods: To carry out posterior capsule opacification (PCO) after cataract surge ry with implantation of two silicone intraocular lenses (IOLs) with different de signs. Methods: We carried out a prospective, clinical study of 116 patients ran domized to standardized phacoemulsification with implantation of The follow-up period was 3 years. To evaluate PCO morp hologically, digital images were obtained and analyzed using the evaluation of poste rior capsule opacification computer software (EPCO). The CeeOnEdge (n = 57) or SI40NB Results: At 2 and 3 years, the eyes with SI40NB I OLs had significantly more PCO than those with the CeeOn Edge IOLs (p = 0.00014 an dp = 0.002). Nine Nd : YAG capsulotomies were performed in the SI40NB group and non e in the CeeOn Edge group. This difference was quite significant (p = 0.003). In some patients a regression of PCO was noticed and confirmed using EPCO. St atistically less PCO was noted w hen the capsulorhexis rim was placed so that it covered all 360 degrees of the optic of the IOL. Conclusions: A clinically and s tatistically significant difference in PCO development between CeeOn Edge and SI 40NB IOLs at 2 and 3 years postoperatively was found. These findings support earlier studies indicating that a sharp edge of the opt ic is a more important factor in IOL design than IOL material in the prevention of PCO.