Wnt信号转导途径与细胞的发育分化密切相关,对正常和肿瘤细胞生长都至关重要,因其启动蛋白为Wnt蛋白而得名[1]。Wnt蛋白是一种由Wnt基因编码的分泌糖蛋白近10余年来的研究表明,Wnt基因及其产物与许多其他相关基因的蛋白质产物构成一条极为复杂的控制从果蝇到人类胚胎发育、细胞 The Wnt signal transduction pathway is closely related to the development and differentiation of cells and is crucial for both normal and tumor cell growth because of its promoter protein Wnt protein. The Wnt protein, a secreted glycoprotein encoded by the Wnt gene For more than a decade, studies have shown that the Wnt gene and its products, along with many other related gene protein products, constitute an extremely complex control of the development of embryos from fruit flies to human embryos,