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结肠癌的家族史已经被证明与发生结肠癌的危险性有关,而所有的癌症家族史(包括结肠癌或其它癌症)对发生结肠癌的危险性的影响还没有进行过详细的分析。本研究的目的是分析发生结肠癌的危险性与结肠癌、直肠癌、乳腺癌、卵巢癌、子宫内膜癌以及前列腺癌等癌症家族史的关系。 病例对照研究利用犹他州人口资料库的资料进行,全部病例(2543例)均为首次原发性结肠癌病人,三级试验组中的每例在出生年份、出生地、婚姻状况和性别等方面均分别与病人相接近。 结果表明,经标准化校验后,其家族中癌症发生率较高的病人发生结肠癌的危险性有所增加(男性OR=2.51,女性OR=2.90),
The family history of colon cancer has been shown to be related to the risk of developing colon cancer, and the impact of all cancer family histories (including colon cancer or other cancers) on the risk of developing colon cancer has not been analyzed in detail. The purpose of this study was to analyze the relationship between the risk of developing colon cancer and the family history of cancer such as colon cancer, rectal cancer, breast cancer, ovarian cancer, endometrial cancer, and prostate cancer. A case-control study was conducted using data from the Utah Population Data Bank. All cases (2543 cases) were patients with primary colon cancer for the first time, and each of the three-stage trial group was born year, place of birth, marital status, gender, etc. All are close to the patient. The results showed that after standardized verification, the risk of colon cancer increased in patients with a high incidence of cancer in their family (male OR = 2.51, female OR = 2.90),