Barakol是从铁刀木Cassia siamea叶和花中提取的成分,具有多种生物活性。由于该植物已用作轻泻药,推断barakol可能通过刺激氯化物分泌和(或)抑制氯化钠透过结肠上皮的吸收,起到缓泻作用。为此作者进行了以下试验。将雄性Wistar大鼠结肠上皮放置Ussing箱,在其顶端和基底外侧进行 Barakol is a component extracted from the leaves and flowers of Cassia siamea and has a variety of biological activities. Since the plant has been used as a laxative, it has been postulated that barakol may act as a laxative by stimulating the secretion of chloride and/or inhibiting the absorption of sodium chloride through the epithelium of the colon. The authors conducted the following tests. Colonic epithelium of male Wistar rats was placed in the Ussing box and performed at the apex and basolateral side