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1 1型糖尿病的治疗背景1型糖尿病(T1DM)是一种以胰岛B细胞永久损伤为主要特征的疾病。患者的典型表现为大量胰岛B细胞损失,血糖调节功能发生异常。T1DM患者的胰岛B细胞损伤常由自身免疫性疾病引发。预计到2030年,全世界成年人(20~79岁)糖尿病发病率将提高到7.7%[1]。2干细胞治疗T1DM干细胞(SCs)是一类多潜能细胞,可分为胚
1 Treatment of type 1 diabetes Background Type 1 diabetes (T1DM) is a disease characterized by permanent damage to islet B cells. The typical manifestation of patients is a large number of islet B cell loss, abnormalities in blood glucose regulation. Islet B cell injury in T1DM patients is often triggered by autoimmune diseases. It is estimated that the prevalence of diabetes in adults worldwide (20-79 years old) will increase to 7.7% by 2030 [1]. 2 stem cell therapy T1DM stem cells (SCs) is a type of pluripotent cells can be divided into embryos