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乙双吗啉(AT—1727)是乙亚胺(ICRF—154)的衍生物,为一双内酰亚胺化合物。药理实验证明其对多种动物可移植性肿瘤具有较明显的抑制作用;对以溶血素为指标的体液免疫有抑制作用,但对以移植物抗宿主反应为指标的细胞免疫则无抑制作
Bimorpholine (AT-1727) is a derivative of ethyleneimine (ICRF-154) and is a bis-imide compound. Pharmacological experiments show that it has a more obvious inhibitory effect on a variety of animal transplantable tumors; hemolysin as an indicator of humoral immunity inhibition, but graft-versus-host response as an indicator of cellular immunity is not inhibited