在闭合性脑外伤特别是额部及眉弓部钝挫伤中 ,额颅底骨折虽未伤及眼球 ,但同侧视力严重减退 ,甚至失明。此种视力丧失称为损伤性视神经病变 ,约占闭合性脑外伤的 2 %～ 1 5 % 〔1〕。目前 ,对本病的治疗仍有争议 ,没有统一的标准。近半年来 ,我们在临床上遇到 4例 ,采用经鼻内 In the closed brain trauma, especially in the frontal and eyebrow arch blunt trauma, although the frontal skull fracture did not hurt the eye, but ipsilateral visual acuity seriously diminished and even blindness. This loss of vision known as the lesion of optic nerve disease, accounting for closed brain injury of 2% to 15% [1]. At present, the treatment of this disease is still controversial, there is no uniform standard. In the past six months, we encountered 4 cases clinically and adopted intranasal