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[目的]探讨青年型缺血性脑血管病(ICVD)的临床特点和危险因素。[方法]选择2008年1月~2011年1月的68例青年型缺血性脑血管病患者作为观察组,对患者的性别、发病年龄、血管影像学检查、预后特点进行分析。另选择同期70例健康青年作为对照组,对两组MT、斑块、TC、TG、HDL-C、LDL-C进行对比研究。[结果]青年型ICVD好发于男性,脑血管成像显示69.2%的患者存在血管狭窄,青年ICVD组MT及斑块检出率明显高于对照组。青年型ICVD患者TC、TG、LDL-C水平明显高于青年健康组,HDL-C明显低于青年健康组。[结论]男性更容易在青年期患ICVD,TC、TG、LDL-C水平与MT呈正相关,针对这些危险因素进行干预可以预防疾病发展,改善患者预后。
[Objective] To investigate the clinical features and risk factors of young type ischemic cerebrovascular disease (ICVD). [Methods] Sixty-eight patients with ischemic cerebrovascular disease from January 2008 to January 2011 were selected as the observation group, and their gender, age of onset, vascular imaging and prognosis were analyzed. Another 70 healthy youths were selected as the control group to compare the MT, plaque, TC, TG, HDL-C and LDL-C in the two groups. [Results] Young ICVD occurred in males. Cerebral angiography showed vascular stenosis in 69.2% of patients. The detection rate of MT and plaque in young ICVD patients was significantly higher than that in control subjects. The levels of TC, TG and LDL-C in young patients with ICVD were significantly higher than those in youth and HDL-C were significantly lower than those in youth. [Conclusion] Men are more likely to have positive correlations with ICVD, TC, TG and LDL-C levels in adolescence, and intervention of these risk factors can prevent disease development and improve prognosis.