糖尿病(Diabetes mellitus,DM)是目前威胁人类健康最重要的非传染性疾病之一,DM患者越来越受到社会的关注,导致DM患者死亡的原因并非DM本身,而是相关并发症。经相关研究调查,约52%的DM患者有至少1种并发症,约25%的DM患者有2种及以上并发症~([1])。目前研究认为DM患者处于一种慢性、非感染性炎症状态,致炎因子发生机制越来越被认同~([2])。近年来,同型半胱氨酸(Homocysteine,Hcy) Diabetes mellitus (DM) is currently one of the most important non-communicable diseases that threaten human health. DM patients are getting more and more social attention. The cause of death in patients with DM is not the DM but the complication. According to relevant research, about 52% of DM patients have at least 1 kind of complications, about 25% of DM patients have 2 or more complications ~ ([1]). The current study suggests that DM patients in a chronic, non-infectious inflammatory state, the mechanism of inflammatory cytokines is increasingly recognized ~ ([2]). In recent years, homocysteine ​​(Homocysteine, Hcy)