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关节炎支原体能粘附至细胞培养中分泌透明质酸的大鼠滑膜细胞,本文阐明其粘附机理。结果表明这一支原体能粘附于大鼠的滑膜成钎维细胞、肺脏细胞、皮肤细胞,但不能粘附于肾脏细胞,提示粘附受体表达或分布于不同的大鼠组织中。对猫肾及初生地鼠肾细胞的粘附不强,而对人胚肺及羊膜细胞亦可发生粘附。2株有毒菌株和2株无毒菌株均能同样粘附于大鼠肺细胞。粘附作用可因胰蛋白酶的消化作用而被抑制,提示主要的粘附素为一种蛋白质。针对4株关节炎支原体的兔抗血清Fab′片段能部分抑制同型或异型菌株的粘附,但抑制的程度有所不同,表明粘附素上仍有不同
Arthritis Mycoplasma can adhere to hyaluronic acid-secreting rat synovial cells in cell culture, the paper elucidates its mechanism of adhesion. The results showed that this mycoplasma could adhere to the rat synovial cells into the lung cells, lung cells and skin cells, but could not adhere to the kidney cells, suggesting that the adhesion receptors were expressed or distributed in different rat tissues. On the cat kidney and primary hamster kidney cell adhesion is not strong, while the human embryonic lung and amniotic cells can also occur adhesion. Two strains of virulent strains and two strains of non-toxic strains can also adhere to rat lung cells. Adhesion can be inhibited by trypsin digestion, suggesting that the major adhesin is a protein. The rabbit antiserum Fab ’fragment against 4 Mycoplasma arthritis was able to partially inhibit the adhesion of homozygous or heterotypic strains, but the degree of inhibition was different, indicating that the adhesin was still different