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目的探讨直肠间质瘤的临床、病理特点及合理治疗方法。方法对1986年6月至 2005年2月收治的19例直肠间质瘤患者的临床、病理学及治疗等临床资料进行回顾性分析。结果 19例中男11例,女8例,平均年龄53．5岁。19例患者诊断均经手术及病理证实。组织学形态以梭形细胞为主,CD117、CD34阳性率分别为100％及74％。高侵袭危险度5例,中侵袭危险度3例,低侵袭危险度4例,极低侵袭危险度7例。结论直肠间质瘤少见,多数倾向于低度恶性生物学行为。治疗以外科手术切除为主。术前获得病理诊断以及术式的选择存在一定困难。对肿瘤直径<3 cm 的低侵袭危险度病例,应经肛门行局部切除术。
Objective To investigate the clinical, pathological features and reasonable treatment of rectal stromal tumors. Methods The clinical data of 19 patients with rectal stromal tumors admitted from June 1986 to February 2005 were retrospectively analyzed. Results 19 cases were 11 males and 8 females, with an average age of 53.5 years. 19 cases were diagnosed by surgery and pathology. Fusiform cell morphology, CD117, CD34 positive rates were 100% and 74%. There were 5 cases with high invasion risk, 3 cases with invasion risk, 4 cases with low invasion risk and 7 cases with very low invasion risk. Conclusion Rectal stromal tumors are rare and most tend to be low-grade malignant. Surgical treatment of the main treatment. Preoperative pathological diagnosis and surgical options there are some difficulties. For cases of low invasion risk of tumor diameter <3 cm, partial resection of the anus should be performed.