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目的探讨胰岛素泵强化治疗(短期)影响新诊断2型糖尿病患者胰岛素分泌、敏感性情况。方法在医院2011年7月—2016年1月期间诊治的2型糖尿病患者中抽取140例作研究对象,对其实施短期胰岛素泵强化治疗,对比治疗前后一般指标、胰岛素分泌和敏感性情况。结果治疗后患者FBG、PG2 h、Hb A1c均较治疗前显著降低(P<0.05),而FINS较治疗前显著升高(P<0.05);治疗后患者HOMA-B水平较治疗前显著升高(P<0.05),而HOMA-IR水平较治疗前显著降低(P<0.05)。结论对新诊断2型糖尿病患者实施短期胰岛素泵强化治疗,可有效改善其胰岛素功能,并增强其胰岛素敏感性,可借鉴。
Objective To investigate the effects of insulin pump therapy (short-term) on insulin secretion and sensitivity in newly diagnosed type 2 diabetic patients. Methods A total of 140 patients with type 2 diabetes diagnosed and treated in the hospital from July 2011 to January 2016 were enrolled in this study. Short-term intensive insulin pump therapy was performed to compare the general indicators before and after treatment, insulin secretion and sensitivity. Results The levels of FBG, PG2h and Hb A1c in patients after treatment were significantly lower than those before treatment (P <0.05), but FINS were significantly higher than those before treatment (P <0.05). After treatment, the levels of HOMA-B were significantly increased (P <0.05), while the level of HOMA-IR was significantly lower than that before treatment (P <0.05). Conclusions Short-term intensive insulin pump therapy for newly diagnosed type 2 diabetic patients can effectively improve insulin function and enhance insulin sensitivity.