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观察L-精氨酸治疗实验家兔蛛网膜下腔出血后的病理生理变化,结果表明:SAH模型制备成后一周,脑组织的含水,Na+量增加,同时脑基底动脉口径缩小,管腔横截面积减少。血管形态学检查提示内皮细胞和平滑肌细胞损伤。用适量L-精氨酸治疗,能显著降低脑组织含水、Na+的量,同时亦能明显扩大脑基底动脉口径。形态学检查提示血管内皮细胞及平滑肌细胞损伤有不同程度的减轻
Arginine treatment of rabbits after subarachnoid hemorrhage observed pathophysiological changes, the results showed that: SAH model prepared one week after the brain tissue water, Na + increased, while the basilar artery caliber narrowing, transverse Cross-sectional area decreases. Vascular morphological examination revealed endothelial and smooth muscle cell damage. Arginine treatment with the right amount, can significantly reduce the water content of brain tissue, Na + volume, but also can significantly increase the diameter of the basilar artery. Morphological examination showed that vascular endothelial cells and smooth muscle cell damage in varying degrees