论文部分内容阅读
目的对学校发生的一起细菌性痢疾暴发疫情进行调查,并采用脉冲凝胶电泳(PFGE)方法对菌株进行同源性分析,为查找传染源、切断传播途径,提供参考依据。方法开展现场流行病学调查,采用描述流行病学的方法对暴发原因进行分析,同时采集患者粪便、水样进行细菌学培养,运用PFGE对分离的菌株进行同源性分析。结果此次暴发疫情的调查共发现病例60例,罹患率为10.12%,发病人群均为小学学生;从53例患者的粪便中共检出30例痢疾阳性病例,且菌群均为宋内志贺菌;水样检测发现2号水井及其旁边的水塘存在宋内志贺菌;对4份病例的粪便、2份水样进行PFGE分析,其结果显示,6份样本所检出菌株的电泳带型完全相同。结论该事件是一起因饮用宋内志贺菌污染的水源而导致的细菌性痢疾暴发疫情。
Objective To investigate the outbreak of bacillary dysentery in schools and to analyze the homology of the strains by pulse gel electrophoresis (PFGE), and to provide a reference for finding the source of infection and cutting off the route of transmission. Methods An epidemiological investigation was conducted in the field. Epidemiological methods were used to analyze the cause of the outbreak. At the same time, faeces and water samples of patients were collected for bacteriological culture. The isolates were analyzed by homology analysis using PFGE. Results The outbreak survey found 60 cases, the attack rate was 10.12%, the incidence of all primary school students; from 53 cases of feces were detected in 30 cases of dysentery positive cases, and the flora were Song Shiga Bacteria were detected by water samples; Shigella sonnei was found in No.2 well and its adjacent pond; PFGE analysis of faeces in 4 cases and 2 water samples showed that the electrophoresis of the strains detected in 6 samples The same type of tape. Conclusion The incident was caused by a bacterial dysentery outbreak caused by drinking water contaminated with Shigella sonnei.