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以左、右及消旋棉酚处理HeLa细胞,发现只有左旋与消旋棉酚具有细胞杀伤作用;左旋棉酚的有效用量为消旋棉酚的一半,提示棉酚的抗肿瘤作用在于左旋光学异构体。
HeLa cells were treated with left and right and racemic gossypol. Only levorotatory and racemic gossypol had cell killing effect. The effective dosage of levogosoglycan was half of racemic gossypol, suggesting that the antitumor effect of gossypol was left-rotating optics. isomer.