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过去对X胸片疑似活动性肺结核的患者一般均要采用患者的痰为标本进行结核菌培养,此方法虽然用了多年,但阳性率并不高。目前推荐γ-干扰素(IFN-γ)释放试验以辅助诊断活动性肺结核,其原理是利用结核杆菌感染者外周血之中存在结核杆菌特异性T淋巴细胞,而这些T细胞一旦再次接触结核杆菌抗原就会发生增殖和分化,从而释放IFN-γ,随后借助ELISA方法检测IFN-γ浓度,统计分泌
In the past, patients with suspected active tuberculosis of X chest radiographs were generally treated with sputum samples of patients for TB culture. Although this method has been used for many years, the positive rate is not high. Currently recommended γ-interferon (IFN-γ) release test to assist the diagnosis of active tuberculosis, the principle is the use of Mycobacterium tuberculosis infection in the peripheral blood of Mycobacterium tuberculosis-specific T lymphocytes, and these T cells once again contact with Mycobacterium tuberculosis Antigen will proliferate and differentiate to release IFN-γ, then detect the concentration of IFN-γ by ELISA,