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目的 探讨足外伤与恶性黑色素瘤的关系。方法 通过对 10例恶性黑色素瘤腹股沟淋巴结转移及足部溃疡的临床病理检查 ,分析足外伤、感染与发生恶性黑色素瘤的关系。结果 经病理证实 10例为腹股淋巴结内恶性黑色素瘤转移 ,1例伴肺转移 ,3例足部溃疡为原发性恶性黑色素瘤 ,其余 7例有足部长期溃疡史 ,全身检查未见原发灶。结论 恶性黑色素瘤的发生可能与足外伤、感染、刺激致皮肤鳞状上皮底层黑色素细胞的增生、恶变有关。当腹股沟淋巴结恶性黑色素瘤转移而找不到原发灶时 ,应注意足部原发溃疡史。我们主张 ,进行外科治疗并辅助放疗、化疗及生物学治疗是必要的。
Objective To investigate the relationship between foot trauma and malignant melanoma. Methods The clinical pathological examinations of 10 cases of malignant melanoma inguinal lymph node metastasis and foot ulcer were performed to analyze the relationship between foot trauma, infection and malignant melanoma. Results Pathologically confirmed in 10 cases of metastatic lymph node metastasis of malignant melanoma, 1 case with lung metastases, 3 cases of foot ulcers as primary malignant melanoma, and the remaining 7 cases had a long history of foot ulcers, body examination did not see the original Hair stove. Conclusion The occurrence of malignant melanoma may be related to the foot hyperplasia, infection, and irritation caused by hyperplasia and malignant transformation of melanin cells in the underlying squamous epithelium of the skin. When the metastasis of the inguinal lymph node metastases to find the primary lesion, attention should be paid to the history of primary ulceration in the foot. We advocate that it is necessary to perform surgical treatment and assist with radiotherapy, chemotherapy, and biological therapy.