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目的 观察美施康定术后镇痛的效果及副作用。方法 选择硬膜外或神经阻滞麻醉 90例。分成手术前服药组 ,手术后疼痛时自行服药组和不服药对照组 ,美施康定用量 6 0mg/次。术后 2、4、8、2 4小时评估VAPS ,记录副作用和处理方法。结果 服药组 4、8、2 4小时VAPS评分明显低于对照组 (P <0 .0 5或P <0 .0 0 1)。术前服药组术中和术后阿片药用量较对照组明显减少 (P <0 .0 5和P <0 .0 1) ,术后服药组恶心呕吐的发出率较高 ,但各组间比较无差异。结论 口服美施康定可用于术后镇痛 ,术前服用能提高镇痛效果 ,可作为术前药使用。
Objective To observe the effect and side effects of postoperative analgesia of metstaining. Methods 90 cases of epidural or nerve block anesthesia were selected. Divided into preoperative medication group, self-administered group and non-medication control group after pain, Meishi Kangding dosage 60 mg/times. VAPS was assessed at 2, 4, 8, and 24 hours after surgery, and side effects and treatment methods were recorded. Results The VAPS scores at 4, 8, and 24 hours in the medication group were significantly lower than those in the control group (P <0.05 or P <0.01). The intraoperative and postoperative doses of opioids in the preoperative medication group were significantly lower than those in the control group (P < 0.05 and P <0.01). The incidence of nausea and vomiting was higher in the postoperative medication group, but among the groups. There is no difference. Conclusion Oral metstaining can be used for postoperative analgesia. Preoperative administration can improve the analgesic effect and can be used as a preoperative drug.