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目的探讨动态血糖监测系统和胰岛素泵在糖尿病合并心肌梗死患者的应用疗效。方法将50例2型糖尿病合并心肌梗死患者随机分为3组:组1采用动态血糖监测系统(CGMS)与胰岛素泵(CSII)结合治疗模式(双C组,16例),组2采用单纯胰岛素泵治疗(CSII组,17例),组3采用胰岛素多次注射治疗(MSII组,17例),后两组采用指端毛细血糖监测法,治疗7d后比较三组血糖控制情况、血糖达标率及血糖漂移情况。结果治疗7天后双C组和CSII组患者的全日血糖、平均血糖(MBG)、平均血糖波动幅度(MAGE)均较治疗前明显下降(p<0.05),明显优于MSII组(p<0.05),低血糖发生次数亦较MSII组明显减少(p<0.05)。其中双C组MBG、MAGE、低血糖次数均显著低于CSII组(p<0.05)。结论胰岛素泵强化治疗可有效控制血糖,动态系统监测系统能监测血糖连续的变化曲线,及时发现高血糖和低血糖,与胰岛素泵联合治疗更有利于心肌梗死患者血糖的控制,降低低血糖的发生率。
Objective To explore the application of dynamic blood glucose monitoring system and insulin pump in patients with diabetes mellitus and myocardial infarction. Methods Fifty patients with type 2 diabetes mellitus complicated with myocardial infarction were randomly divided into three groups: Group 1 was treated with combination of CGMS and CSII (group C, 16 patients), group 2 was treated with insulin alone (CSII group, n = 17). Group 3 received multiple injections of insulin (MSII group, n = 17). The latter two groups were monitored by fingertip capillary blood glucose monitoring. After 7 days of treatment, And blood glucose drift. Results The blood glucose, mean blood glucose (MBG) and mean arterial blood glucose (MAGE) in patients with double C and CSII were significantly lower than those before treatment (P <0.05) after 7 days of treatment, , The number of hypoglycemia also significantly reduced compared with MSII group (p <0.05). The double C group MBG, MAGE, low blood sugar frequency were significantly lower than the CSII group (p <0.05). Conclusion Insulin pump intensive therapy can effectively control blood glucose. The dynamic system monitoring system can monitor continuous changes of blood glucose and detect hyperglycemia and hypoglycemia in time. Combined with insulin pump is more beneficial to the control of blood glucose in patients with myocardial infarction and reduce the occurrence of hypoglycemia. rate.