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目的研究血红素铁胶囊对人体缺铁性贫血的改善情况。方法选择男性血红蛋白含量小于130g/L和女性血红蛋白含量小于120g/L的受试者118名,分为试食组和对照组。试食组每人每天6粒服用受试样品,连续30d,对照组按同法给予安慰剂。比较试验前后血红蛋白、血清铁蛋白、红细胞内游离原卟啉含量变化。结果试食组血红蛋白含量平均升高23.6g/L(22.24%),血清铁蛋白含量平均升高34.1μg/ml(75.78%),红细胞内游离原卟啉平均降低0.09μmol/L(10.11%),通过配对t检验及成组t检验比较,差异均有统计学意义(P<0.01)。结论在研究剂量范围内可见血红素铁胶囊具有改善人体缺铁性贫血的功能。
Objective To study the effect of heme iron on the improvement of human iron deficiency anemia. Methods 118 subjects with male hemoglobin less than 130g / L and female hemoglobin less than 120g / L were selected and divided into trial group and control group. Test group 6 tablets per person per day to take the test sample for 30 days, the control group were given the same method of placebo. Before and after the comparison of hemoglobin, serum ferritin, erythrocyte free protoporphyrin content changes. Results The average hemoglobin content of test group increased by 23.6 g / L (22.24%), the average serum ferritin level increased by 34.1 μg / ml (75.78%), and the average free erythrocyte protoporphyrin decreased by 0.09 μmol / L (10.11% , The difference was statistically significant (P <0.01) by paired t test and group t test. Conclusion It can be seen in the study dose range that heme iron capsule has the function of improving human iron deficiency anemia.