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对96例病毒性肝炎患者检测了血清TNF-α、IL-6水平。结果各型病毒性肝炎血清IL-6值及TNF-α值均较正常人显著增高,IL-6伴随着慢性化程度和病情加重而逐渐增高;血清TNF-α、IL-6之间具有良好的相关性,且随着病情加重和疾病发展其相关性愈加明显。说明IL-6可作为病毒性肝炎病情轻重和慢性化发展的判断指标。
Serum levels of TNF-α and IL-6 were measured in 96 patients with viral hepatitis. Results Serum levels of IL-6 and TNF-α in various types of viral hepatitis were significantly higher than those in normal controls. The level of IL-6 was gradually increased with the severity of exacerbations and chronic conditions. The serum levels of TNF-α and IL-6 were good Of the correlation, and as the disease exacerbates and the development of the disease the more obvious its relevance. That IL-6 can be used as a marker of the severity of viral hepatitis and chronic disease development.