重症肌无力是由于神经肌肉运动终板触突后膜的菸酰乙酰胆碱受体的传导为循环抗体所阻滞,致使受体数日减少,运动后骨胳肌极度无力和疲劳。它可与胸腺瘤并存或单独存在。伦敦医院1960～1979年曾治疗50例重症肌无力病人,其中48例有完整记录。年龄10～72岁。女31,男17。病史7天至10年(平均20.2个月)。按症状可分为三组:(1)眼部症状(65％),或为唯一症状,或伴其他症状;(2)咽喉和口腔症状(56％);(3)全身症状(60％),如面肌无力,全身无力和呼吸困难。耳鼻喉方面的肌无力,本组咽下困难为56％,呼吸困难为29％。喉部受累在长时间说话时可出现逐渐加重的波动性呼吸困难,声带闭合不良致 Myasthenia gravis is due to blockage of neuromuscular motor postsynaptic membrane nicotinic acetylcholine receptor conduction blocked by circulating antibodies, resulting in decreased receptor days, extremely weak after exercise and weakness and fatigue. It can co-exist with thymoma or exist alone. London Hospital from 1960 to 1979 had treated 50 patients with myasthenia gravis, of which 48 have a complete record. Age 10 to 72 years old. Female 31, male 17. A history of 7 days to 10 years (average 20.2 months). Symptoms can be divided into three groups: (1) ocular symptoms (65%), or the only symptoms, or with other symptoms; (2) throat and mouth symptoms (56%); , Such as facial weakness, general weakness and breathing difficulties. ENT aspects of muscle weakness, the group of dysphagia was 56%, dyspnea was 29%. Throat involvement in prolonged speech can occur when the gradual aggravating dyspnea, bad vocal cord closure