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血管生成拟态是指具有可塑性、侵袭性的肿瘤细胞所形成的非内皮细胞衬覆的微血管通道,其在体内显示为过碘酸席夫染色阳性和CD31染色阴性的图案,在体外三维培养体系中显示为管状或图案样的网络,其可能与肿瘤的侵袭转移潜能以及较差的临床预后有关。
Angiogenic mimicry refers to a non-endothelial cell-capped microvascular canal formed by a malleable, invasive tumor cell that appears in vivo as a Schiffl-positive and CD31-stained negative pattern in an in vitro three-dimensional culture system Appear as a tubular or pattern-like network that may be related to tumor invasion and metastasis potential as well as poor clinical prognosis.