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应激性溃疡出血是危重病人的一个严重并发症,死亡率高达50％,治疗常较困难。我们在近2年中遇4例,经多种非手术治疗无效后加用奥美拉唑(Omeprazole,简称OME)即洛赛克Losec制止了出血,现报道如下。例1.雪△,男,58岁,因肝右后叶原发癌于 1989年12月2日经腹行右半肝切除,术中误伤下腔静脉,开右胸缝合下腔静脉破口。术中失血近10000ml,血压降至5/1kPa,经大量输血、补液1小时后回升至14/10kPa。术后给凝血酶元复合物,纤维蛋白元,葡萄糖酸钙,维生素K、C及止血环酸。术后
Stress ulcer bleeding is a serious complication of critically ill patients, the mortality rate as high as 50%, the treatment is often more difficult. We encountered in 4 cases in the past 2 years, after a variety of non-surgical treatment is invalid with Omeprazole (Omeprazole, referred to as OME) that is, Losec to stop bleeding Losec, are reported below. Example 1 snow △, male, 58 years old, due to the right posterior lobe of the primary cancer on December 2, 1989 through the right abdominal hemihepatectomy, intraoperative mistakenly invaginated vena cava, open the right thoracic suture vena cava . Intraoperative blood loss nearly 10000ml, blood pressure dropped to 5 / 1kPa, after a large number of blood transfusion, rehydration 1 hour after the recovery to 14 / 10kPa. Postoperative thrombin metformin, fibrin, calcium gluconate, vitamin K, C and tranexamic acid. After surgery