论文部分内容阅读
目的对某核电站工人超重、肥胖、代谢综合征、前驱糖尿病、糖尿病发生率进行横断面调查。方法收集该核电站1388名在职工人的健康检查资料,超重、肥胖、代谢综合征、前驱糖尿病、糖尿病分别按WHO和美国国家胆固醇教育计划有关标准诊断。结果核电站在职工人(21~59岁)年龄标化的超重和代谢综合征发生率分别为37.50%(95%可信区间34.95%~40.05%)和14.02%(95%可信区间12.16%~15.88%),均高于中国成年人群水平(P<0.01);年龄标化的肥胖发生率为3.27%(95%可信区间2.33%~4.21%),与中国成年人群水平差异无统计学意义(P>0.05);年龄标化的前驱糖尿病和糖尿病发生率分别为5.14%(95%可信区间3.98%~6.30%)和2.70%(95%可信区间1.85%~3.55%),均低于中国成年人群水平(P<0.01)。1~9 a和10~19 a工龄组工人超重发生风险分别是<1a工龄组工人的2.94倍(95%可信区间1.23~7.06)和3.50倍(95%可信区间1.37~8.91)。工人超重和代谢综合征发生率均随工龄增高呈显著上升趋势(P趋势<0.01)。结论该核电站工人发生超重和代谢综合征的风险较高,这是否与接触核素辐射有关仍有待进一步研究。
Objective To carry out a cross-sectional survey on the incidence of overweight, obesity, metabolic syndrome, prediabetes and diabetes in a nuclear power plant. Methods The health checkup data of 1,388 active workers at the NPP were collected. Overweight, obesity, metabolic syndrome, prediabetes and diabetes were diagnosed according to WHO and the National Cholesterol Education Program. Results The age-standardized prevalence rates of overweight and metabolic syndrome were 37.50% (95% confidence interval 34.95% -40.05%) and 14.02% (95% confidence interval 12.16% ~ 15.88%, respectively) were higher than those in China (P <0.01). The incidence of obesity was 3.27% (95% confidence interval 2.33% -4.21%), which was not significantly different from the adult population in China (P> 0.05). The age-standardized prevalences of pre-diabetes and diabetes were 5.14% (95% confidence interval 3.98% -6.30%) and 2.70% (95% confidence interval 1.85% -3.55%, respectively) The level of adult population in China (P <0.01). The risk of overweight among workers in the 1 ~ 9 a and 10 ~ 19 a working age groups was 2.94 times (95% confidence interval 1.23 ~ 7.06) and 3.50 times (95% confidence interval 1.37 ~ 8.91), respectively. The incidence of overweight and metabolic syndrome in workers both increased significantly with increasing seniority (P trend <0.01). Conclusion The risk of overweight and metabolic syndrome is high for workers at this nuclear power plant. Whether this is related to exposure to radionuclide remains to be further studied.