转移是恶性肿瘤的基本生物学特性 ,肿瘤在手术治疗后尚有 4 0 %～ 6 0 %的患者复发和转移。肿瘤侵袭转移过程具有多步骤多阶段多因素的特点。涉及肿瘤血管的形成 ,与细胞及基质之间的相互粘附 ,降解及肿瘤细胞的运动等。本文就胃癌侵袭转移多个相关因素的研究进展作一总结 Metastasis is the basic biological characteristics of malignant tumors, tumor recurrence and metastasis after surgery in 40% ~ 60% of patients. The process of tumor invasion and metastasis has the characteristics of multi-step, multi-stage and multi-factor. Involved in the formation of tumor blood vessels, and cells and matrix adhesion between each other, degradation and tumor cell movement. This article summarizes the research progress of multiple related factors of gastric cancer invasion and metastasis