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目的探讨首次热性惊厥患儿与流感病毒A型感染的关系及其临床特征。方法采用直接免疫荧光法对60例首次热性惊厥的住院患儿进行流感病毒A型检测,并比较感染流感病毒A型(流感组)与未感染流感病毒A型(非流感组)的热性惊厥患儿的临床特征。结果流感组患儿的平均年龄显著高于非流感组(P<0.01);流感组中,年龄>3岁的患儿显著多于非流感组(P<0.01)。热性惊厥发作时,流感组比非流感组的体温更高(P<0.01)。结论流感病毒A型感染与大龄儿童尤其是学龄前儿童的热性惊厥发作密切相关。
Objective To investigate the relationship between influenza A virus infection and clinical features in children with first febrile seizures. Methods Direct immunofluorescence was used to detect influenza A virus in 60 infants with first febrile seizures and compared the febrile seizures between the influenza A (influenza) group and the uninfected influenza A (non-flu) group Clinical characteristics of children with convulsion. Results The mean age of children in the flu group was significantly higher than that in the non-flu group (P <0.01). In the flu group, the number of children aged> 3 years was significantly higher than that of the non-flu group (P <0.01). At the onset of febrile seizures, body temperature in the flu group was higher than in the non-flu group (P <0.01). Conclusion Influenza A infection is closely related to the onset of febrile seizures in older children, especially in preschool children.