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目的:研究广西血竭的消炎止痛等药理作用。方法:运用巴豆油、角叉菜胶致炎、小鼠扭体反应等药理学方法。结果:广西血竭外擦能明显抑制巴豆油引起的小鼠耳壳炎症、大鼠角叉菜胶性足肿胀,降低小鼠腹腔毛细血管通透性;ig减少小鼠扭体反应次数,对抗己烯雌酚引起的大鼠在位子宫收缩作用。大鼠ig30d未出现毒性反应,诸脏器均未见异常现象。结论:实验结果表明,广西血竭具有明显的抗炎、镇痛作用,毒性很低。
Objective: To study the anti-inflammatory analgesic and other pharmacological effects of Xue-qi in Guangxi. Methods: The use of croton oil, carrageenan induced inflammation, writhing in mice and other pharmacological methods. Results: External Exhaustion of Radix Rehmanniae could inhibit the inflammation of the mouse ear shell induced by croton oil, the carrageenan foot swelling in rats and the peritoneal capillary permeability of mice; ig reduced the number of writhing reaction in mice, Diethylstilbestrol induced rat contractile activity in the uterus. Ig30d rats did not appear toxic reaction, no abnormalities in all organs. Conclusion: The experimental results show that the blood of Guangxi has obvious anti-inflammatory, analgesic effect, low toxicity.