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广泛使用DDS单疗已使麻风治疗发生了革命性转变,某些地区已使麻风接近于被控制,即新的多菌型病人越来越少,残废病人也大大减少。但许多地区都出现了耐药的病例。联合化疗的目的就在于防止或克服耐药现象,提供一种更快、更有效,且疗期更短的疗法。联合化疗用于多菌型,至少两年,最好直到细菌阴转;用于少菌型可半年或1年。要评价联合化疗的效果,特别是对复发率的影响为时尚早,还要有几年的实验;最乐观的估计是它可供病人的带菌总量减少,特别是迅速减少需要治疗的少菌型病人数。作
The widespread use of DDS monotherapy has revolutionized the treatment of leprosy, and in some areas leprosy has been brought under control, with fewer and fewer new multi-bacteria patients and fewer patients with disability. However, drug-resistant cases have emerged in many areas. The goal of combined chemotherapy is to prevent or overcome drug resistance and to provide a faster, more effective and shorter-term therapy. Combination chemotherapy for multi-fungal, at least two years, preferably until the bacteria overcast; for less bacteria can be six months or a year. It is too early to assess the effect of combination chemotherapy, especially on the relapse rate, and several years of experimentation; the most optimistic estimate is that it reduces the total amount of bacteria available to patients, especially rapidly reducing the number of bacteria requiring treatment Type of patients. Make