肝炎相关再障病情重,大多在非甲非乙型肝炎后发生,中数生存期常小于6个月,90%的患者在1年内死亡。肝炎引起骨髓衰竭的机理不清,可能与异常的细胞或体液免疫有关。作者等用HLA相合、混合淋巴细胞培养阴性的同胞骨髓对5例肝炎相关再障进行骨髓移植,移植前用环磷酰胺作预处理,其中3例加用全身淋巴照射。患者从肝炎发病到发生再障的中数时 Hepatitis-related aplastic anemia, mostly in non-A non-B hepatitis, the median survival is often less than 6 months, 90% of patients died within 1 year. The mechanism by which hepatitis causes bone marrow failure is unclear and may be related to abnormal cellular or humoral immunity. Authors such as HLA-matched, mixed lymphocyte negative fellow bone marrow of 5 cases of hepatitis-related aplastic anemia bone marrow transplantation before transplantation with cyclophosphamide for pretreatment, of which 3 cases plus systemic lymphatic irradiation. Patients from the onset of hepatitis to aplastic anemia in the median