作者根据以往动物试验证明:严重的兔角膜硷烧伤性溃疡和穿孔是由于角膜所产生的分解胶原的酶(Collagenolytic enzyme)而引起。角膜细胞接触硷之后立即被破坏,7—10天后,重新生长的上皮细胞和再次组成基质的细胞产生一种能使角膜发生溃疡的胶原酶(Collagenase)。用胶原酶抑制剂来治疗急性兔角膜硷烧伤可避免溃疡形成。Brawn等用胶原酶抑制剂、半胱氨酸(Cystein)治疗局部硷烧伤或有溃疡形成的角膜硷烧伤21只限获得良好疗效。因为硷烧伤后 Based on previous animal studies, the authors demonstrated that severe corneal alkali burn burns and perforation are caused by collagen-degrading enzymes produced by the cornea. Corneal cells are destroyed immediately upon exposure to the base. After 7-10 days, the newly growing epithelial cells and the cells that make up the matrix again produce a collagenase that causes the corneal ulcer to develop. Treating Acute Corneal Alkaloid Burn with Collagenase Inhibitors Avoids Ulcer Formation. Brawn and other collagenase inhibitors, cysteine ​​(Cystein) treatment of local alkali burns or ulcer formation of corneal alkali burn 21 only get good results. Because after the alkali burn