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目的探讨大肠腺瘤癌变的临床危险因素。方法回顾性分析592例大肠腺瘤及癌变病例与腺瘤大小、发生部位、形态、病理类型的关系。结果 592例大肠腺瘤患者发生癌变者为36例,癌变率为6.1%,绒毛状腺瘤癌变率最高,管状腺瘤癌变率较低;直肠腺瘤癌变率均高于右半结肠(P﹤0.05);大肠腺瘤癌变率随着腺瘤的增大而升高,并且广基形腺瘤比长蒂形腺瘤更易癌变。结论大肠腺瘤癌变与腺瘤大小、解剖部位、外形及病理类型等因素有关。
Objective To investigate the clinical risk factors of colorectal adenoma. Methods A retrospective analysis of 592 cases of colorectal adenoma and cancer cases and adenoma size, location, morphology, pathological types. Results Among 592 cases of colorectal adenoma, 36 cases were carcinomatous, the rate of carcinogenesis was 6.1%, the rate of carcinogenesis of villous adenoma was the highest, the rate of tubular adenoma was lower, and the rate of rectal adenoma was higher than that of right half colon (P < 0.05). The rate of colorectal adenocarcinoma increased with the increase of adenoma, and wide acrosomal adenoma more easily than carcinoid adenoma. Conclusion Colorectal adenoma carcinogenesis and adenoma size, anatomical location, shape and pathological type and other factors.