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目的：探讨“以问题为中心（PBL）”教学法在临床药师师资培训中的应用效果。方法：介绍 PBL 教学法在师资培训中的具体实施内容、流程与组织方法。结果：经过科学的成绩分析，结果显示学员培训前和培训后相比理论考试成绩平均提高30分，临床实践成绩平均在85分以上。充分体现了出培训班教学效果显著，教学方案设计合理。结论：PBL 教学法在临床药师师资培训中的首次应用受到大家的一致好评。认为该方法不但提高了学习的目的性与趣味性，还能让学员有针对性地去探索并运用理论知识，以提高分析和解决问题的能力，更能更加系统牢固的掌握理论知识并与临床需求紧密结合，值得推广。“,”Objective:To evaluate the effects of problem-based learning(PBL)mode in the clinical pharmacist teacher training. Methods:The specific implementation content,process and organizational methods of PBL mode were introduced in the clinical pharmacist teacher training. Results:Through the scientific analysis on the student marks,the results showed that the theoretical test scores of the students were increased by average 30 points when compared with those before the training,and the average score of clinical practice was more than 85 points. The achievement fully reflected the significant effect of PBL teaching courses and the reasonable design of teaching plan. Conclusion:The first application of PBL mode in the clinical pharmacist teacher training was welcomed by all the students. The teaching method not only improves the purpose and funny of learning,but also allows students to explore a targeted manner and apply theoretical knowledge in order to improve the analysis and problem-solving skills,and obtain more systematic and solid theoretical knowledge to closely integrate with the clinical needs, therefore,PBL mode is worthy of promotion.