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目的:比较肿瘤标志物联合螺旋CT扫描与PET/CT全身代谢显像对肺癌诊断及分期准确率的区别。方法:选择手术或穿刺活检确诊为肺癌,且术前行螺旋CT扫描并有血清学肿瘤抗原检测或PET/CT扫描的患者,比较两种方法对肺癌的检出率以及对肺癌分期的影响。结果:肿瘤抗原检测联合CT扫描与PET/CT显像对肺癌诊断相符率分别为67.44%和90.70%,肺癌局部病灶显示阳性率分别为86.05%和95.35%,对纵隔淋巴结检出的阳性率分别为65.12%利83.72%,同时PETCT显像检出肿瘤标志物联合CT扫描未发现的6例远处转移;与CT扫描相比,PETCT显像使43例患者的临床分期提前11.63%,推后16.28%,使9.3%(4例)的患者改变了治疗方式。结论:PETCT全身代谢显像比血清学检查肿瘤抗原联合CT扫描对肺癌的诊断阳性率更高,且对肺癌的分期更加准确,PETCT全身代谢显像是诊断肺癌及进一步明确肺癌分期的一种良好方法。
Objective: To compare the diagnostic accuracy and staging accuracy of lung cancer with tumor markers combined with spiral CT scan and PET/CT systemic metabolic imaging. METHODS: Patients with lung cancer diagnosed by surgery or needle biopsy were selected, and patients who had undergone spiral CT scan and serological tumor antigen detection or PET/CT scan before surgery were compared for the detection rate of lung cancer and the effect on lung cancer staging. Results: The coincidence rates of tumor antigen detection combined with CT scan and PET/CT scan for lung cancer were 67.44% and 90.70%, respectively. The positive rates for local lung cancer showed 86.05% and 95.35%, respectively. The positive rates for detection of mediastinal lymph nodes were It was 65.12% and 83.72%. Simultaneous PETCT imaging detected 6 distant metastases that were not detected by combined CT scan of tumor markers. Compared with CT scan, PETCT imaging advanced the clinical staging of 43 patients by 11.63%. 16.28%, 9.3% (4 patients) changed the treatment. Conclusion: PETCT systemic metastasis imaging is more accurate than lung cancer and serological antigen combined with CT scan in the diagnosis of lung cancer, and the staging of lung cancer is more accurate. PETCT systemic metabolic imaging is a good diagnosis of lung cancer and further clarify the staging of lung cancer is a good method.