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血钙过低或过高可导致精神病理状态。近年Carman等证实,脑脊液和血浆中钙浓度的变化对情绪的调节起有重要作用。作者报告1例在纠正低钙和低镁的替代治疗中导致的躁狂发作。 病例:女,35岁,因低钙和低镁伴发精神障碍住院。既往曾因抑郁症用阿米替林和丙咪嗪治疗,但无躁狂发作中和情感性精神病家族史。73年因肥胖症行空回肠旁路手术,后由于肠梗阻切除部分肠段发生短肠综合征。需每日服用NaHCO_3、KCl、CaCO_3、叶酸盐和肌注硫酸镁每周1g。入院前4周因局部疼痛停止注射MgSO_4,当时血镁1.1mEq
Low or high serum calcium can lead to psychopathology. In recent years, Carman et al confirmed that changes in cerebrospinal fluid and plasma calcium concentration play an important role in the regulation of emotion. The authors report 1 case of an episode of mania resulting from the correction of hypocalcemic and hypomicronic replacement therapy. Case: Female, 35 years old, hospitalized for mental retardation due to low and low magnesium. Historically, amitriptyline and imipramine have been used for depression, but no manic episode neutralizes the family history of affective psychosis. 73 years due to obesity empty ileum bypass surgery, after intestinal resection due to bowel short bowel syndrome occurred. Take daily NaHCO_3, KCl, CaCO_3, folic acid and intramuscular injection of magnesium sulfate 1g weekly. Four weeks before admission, MgSO 4 was stopped due to local pain when blood magnesium was 1.1 mEq